Thank you for the suggestions, unfortunately I'm still in the same situation. I have disabled antivirus entirely when trying to run the game, I verified Avorion and AvorionServer were both allowed through the firewall. I also confirmed that nvidia drivers automatically recognized Avorion, and even tried to manually force it to run OpenGL under the 1080ti card. No luck sadly. Is there any other detail from a log somewhere I could grab to help troubleshoot?
I have also tried reinstalling the game entirely, but got the same results.